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Medarex's expertise in making antibody based drugs could help Bristol Myers as it strives to regain its stature as one of the world's leading players in the oncology market, and to develop treatments for immunologic conditions such as arthritis, lupus and psoriasis.Medarex has developed so called "transgenic" mice with human immune systems that are able to generate fully human antibodies that can be used as drugs."The premium is not out of whack when you look at the scarcity value of this technology and the appetite for biotech companies right now," a source familiar with the deal told Reuters. "It's a small deal in size but a large deal in terms of the potential scope they gain with this science."Bristol Myers and Medarex are developing one of the mouse generated antibodies, called ipilimumab, as a treatment for patients in late stages of melanoma the most deadly form of skin cancer. There are now no highly effective treatments for it.In three mid stage clinical trials, 30 to 42 percent of patients with metastatic melanoma treated with ipilimumab were still alive after two years, which Bristol Myers said established a survival benefit.
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